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A-PVP (Alpha-Pyrrolidinopentiophenone) — Research Chemical Overview
Synonyms
- Alpha-Pyrrolidinopentiophenone
- 1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone
- α-PVP / A-PVP
- Alpha-Pyrrolidinovalerophenone
- O-2387
- β-Ketone-Prolintane
- Prolintanone
CAS Number
102-97-6
Molecular Formula & Structure
- Formula: C₁₆H₂₂N₂O
- Chemical Class: Substituted pyrrolidinophenones (cathinone family)
- Structure: A β-ketone analog structurally related to pyrovalerone and prolintane.
Purity & Analytical Grade
- Purity: ≥ 98% (research/analytical grade)
- Intended Use: Laboratory, forensic, and analytical reference purposes only.
Physical & Chemical Properties
- Appearance: White crystalline or off-white crystalline powder
- Melting Point: ~132–135°C
- Solubility: Soluble in common organic solvents such as ethanol, methanol, and acetone
- Stability: Stable under recommended storage conditions; sensitive to moisture and direct sunlight
Safety & Handling Information
A-PVP is a laboratory-grade research compound and should be handled only by trained professionals.
Hazards
- May cause skin irritation
- May cause eye irritation
- May cause respiratory irritation
- Avoid ingestion or inhalation
Personal Protective Equipment
- Nitrile gloves
- Laboratory coat
- Protective goggles
- Work only in a well-ventilated or controlled lab environment
First-Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms continue
- Skin Contact: Wash with water and mild soap
- Eye Contact: Rinse eyes for 10–15 minutes; consult a medical professional
- Ingestion: Seek immediate medical assistance
Research Uses & Applications
A-PVP is widely examined in scientific and forensic sectors due to:
Primary Research Areas
- Analytical reference standard
- Forensic toxicology
- Pharmacological modelling
- Comparative studies with related pyrrolidinophenone analogs such as pyrovalerone and prolintane
A-PVP is not intended for human or veterinary use and should not be used outside strictly controlled research environments.
Regulatory Information
Regulation varies by region.
A-PVP may be listed as a controlled substance in many jurisdictions due to its historical appearance in toxicology casework and recreational misuse.
Researchers must ensure compliance with all local, national, and international regulations before acquiring or handling the substance.
Storage Guidelines
- Keep in a cool, dry environment
- Store away from sunlight
- Keep container tightly sealed
- Avoid humidity exposure
Extended Chemical Background
A-PVP (α-pyrrolidinovalerophenone) belongs to the same chemical group as pyrovalerone and prolintane and is classified as a stimulant-type cathinone analog.
It is a β-keto derivative of prolintane, which influences its structural and analytical profile.
Pyrovalerone, one of its closest analogs, is known to inhibit dopamine and norepinephrine transporters, and A-PVP is often studied for similar mechanistic behavior in laboratory simulations.
Meta Description (Rank-Math Optimized)
Discover A-PVP (Alpha-Pyrrolidinopentiophenone), a high-purity research chemical used for analytical, forensic, and laboratory applications. Learn about its molecular structure, properties, safety guidelines, and storage requirements.
FAQ
1. What is A-PVP?
A-PVP is a synthetic pyrrolidinophenone compound used exclusively for laboratory, analytical, and forensic research.
2. What is the purity of A-PVP?
It is typically supplied at ≥98% analytical grade, suitable for advanced laboratory studies.
3. Is A-PVP the same as A-PHP?
No. A-PVP and A-PHP are related pyrrolidinophenones but differ in their carbon chain length and chemical behavior. Researchers often compare these compounds in structural and analytical modelling studies.
4. How should A-PVP be stored?
In a cool, dry, sealed container, away from heat and direct sunlight.
5. Is A-PVP for human use?
No. A-PVP is not for human consumption and is intended solely for controlled scientific research.

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